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doi: 10.1161/CIRCULATIONAHA.119.041659 68 XieYBoweBXianHLouxTMcGillJBAl-AlyZ
DeVivo DC: Effect of L-carnitine treatment for valproate-induced hepatotoxicity
Population-wide observational studies provide a good and generalisable estimation of clinical effects with modest confidence, thus defining the clinical roles of each antidiabetic drug class more clearly
Pramlintide (approved 2005): three-amino-acid substitution enabling solubility, 2-3 daily dosing before meals, approximately 23% weight loss in T2D
