All experiments with mice were performed according to the protocols approved by the Committee of Animal Experiments of Osaka University (approval number 02-001-003), in accordance with the National Institutes of Health Guide for Care and Use of Laboratory Animals
For example, Borges et al
Do not use Zepbound if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC)
To characterize the class-level safety profile, K-Dense Web performed a Proportional Reporting Ratio (PRR) disproportionality analysis using the openFDA FAERS API, comparing semaglutide and tirzepatide across six safety signals from 2020 through April 2026
Researchers took a closer look at the results after the main study was completed, and these findings were shared at a major medical conference (the EASD congress) in September 2025
Real-World Evidence of GLP-1 RA Therapy in T2D A substantial body of data in real-world settings supports the efficacy and safety of GLP-1 RAs evidenced from the randomised controlled trials (RCTs)