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meaning that animal studies have shown some adverse effect or there are no well-controlled studies in humans, but potential benefits may warrant use despite potential risks

Journal of Neurology, Neurosurgery, and Psychiatry

peripheral vascular thrombosis Hematological : Polycythemia vera (a rare type of blood cancer) Gastrointestinal : Mild, transient diarrhea Dermatological : Itching

The symptoms can be Tingling or burning sensation in hands, arms and legs A loss of balance and decreased coordination Weakened muscles Uncontrollable sweating More Peripheral neuropathy symptoms below You should take great care to prevent further damage, as ignoring symptoms can have long-term consequences

Persistently high results could signal a blood disorder, a malignancy or a problem with the liver or kidneys

for neutral grounding on indications and biology, see Vitamin B12 Health Professional Fact Sheet , which outlines deficiency care and dosing context for clinicians