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Preclinical evidence strongly indicates that BPC-157 modulates this critical signaling pathway, leading to a cascade of downstream effects essential for tissue repair (Sikiric et al., J Physiol Paris , 2012)

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Note that human-interest senolytic dosing is usually pulsed/intermittent (a few consecutive days per cycle), so this continuous schedule diverges from the typical senolytic paradigm

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Effects of dexamethasone on the availability of L-tryptophan and on the insulin and FFA concentrations in unipolar depressed patients Biol Psychiatry 1990

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