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A meta-analysis of 17 prospective studies (N=29,649) found that men in the highest IGF-1 quartile had an odds ratio of 1.49 (95% CI 1.14-1.95) for prostate cancer compared with the lowest quartile [8]
It also plays a crucial role in regenerating other antioxidants like vitamins C and E
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Vitamin C (Sodium Ascorbate): Enhances the absorption of glutathione and boosts immunity
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The acetylation of SP1 at K19 increases its protein stability and transcriptional activity, affecting polyamine metabolism through the ACSS2SP1SAT1 axis, and promoting the occurrence and progression of tumors
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