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The current best practice is risk-based shared decision-making rather than universal discontinuation
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PMCID: PMC10338287
Compare that to the STEP 1 extension data, where participants regained 11.6 percentage points within 52 weeks of stopping semaglutide without any structured dietary intervention
By integrating real-time hormonal lab results, genetic markers, and reported side effect data, an AI model could help predict a patient's sensitivity to the medications and potentially recommend a slower, more cautious titration schedule or a lower maintenance dose from the start, minimizing discontinuation rates and improving adherence
Among them, GLP-1RA was identified as the suspected drug causing suicide/self-injury in 534 reports
