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Farxiga's role in non-diabetic weight management remains complementary rather than primary

The ravagalimab Phase 2 single-arm study evaluated this anti-CD40 monoclonal antibody in moderate to severe UC patients by constructing synthetic placebo control groups using two approaches: first, a Bayesian method incorporating historical placebo data from meta-analyses of tofacitinib, ustekinumab, and upadacitinib pivotal trials, taking advantage of objective centrally-read endoscopies and low placebo endoscopic improvement rates

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The study showed that patients taking semaglutide were 24% less likely to experience major kidney problems compared to those taking a placebo, and they also had a lower risk of death