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The New England Journal of Medicine , 387(4), 327-340
Further, the biosynthesis of Sec on tRNA [ser]Sec starts with the loading of a serine residue on tRNA [ser]Sec followed by its phosphorylation through the enzyme O-phosphoseryl-tRNA [Ser]Sec kinase (PSTK) to form phosphoseryl-tRNA [Ser]Sec
a , Mitochondrial oxygen consumption rate (OCR) during mitochondrial stress test of healthy primary murine hepatocytes treated ex vivo for 4h with 100 nM cotadutide, g1437 or liraglutide compared to vehicle control hepatocytes (n=3 biologically independent samples/group)
"I think [generics are] a big game changer," said Brian Rodrigues, a professor in the faculty of pharmaceutical sciences at the University of British Columbia