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Sources Disclaimer: This article is for general nutrition education only and is not medical advice

Ferrannini, E., Rosenbaum, M

The mechanism of action involves several key effects: Enhanced insulin secretion : GLP-1 medications stimulate the pancreas to release insulin in a glucose-dependent manner, meaning they work primarily when blood glucose levels are elevated

Additionally, there have been case reports and anecdotal evidence suggesting that GLP-1 drugs can negatively impact mood

A vicious cycle unfolds from there: Carrying more weight may pump up the size of your fat cells and trigger inflammation, both of which can make it even tougher for your cells to respond to insulin