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In the development of the GLP-1 receptor agonist, semaglutide, the strategy used to extend the drugs half-life was to promote covalent and non-covalent binding of semaglutide to albumin through the addition of a fatty-acid attachment on semaglutide
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Willesen et al., 1999
In 1968, in response to a few athlete deaths that were believed to be linked to P.E.D
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