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Retatrutide Heart Rate Increase: Mechanism, Evidence, and Clinical Guidance Retatrutide heart rate increase is an important safety consideration for this investigational triple agonist, which simultaneously targets GLP-1, GIP, and glucagon receptors
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Whilst there is no formal contraindication to using Ozempic with Hashimoto's disease, careful clinical assessment, individualised monitoring, and potential adjustments to thyroid hormone replacement are essential
In rabbits and cynomolgus monkeys administered semaglutide during organogenesis, early pregnancy losses or structural abnormalities were observed at clinical exposure (rabbit) and 2-fold the MRHD (monkey)
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