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3.2 NAC enhances the osteogenic activity of precursor cells in the bone immune microenvironment Primary MSCs closely reflect the biological behavior of niche cells and are both ideal seeding cells and cell models in bone tissue engineering

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Taken together, the researchers concluded that thyroid function may affect mast cells, and that mast cell degranulation could affect thyroid function.[ref] In patients with autoimmune thyroid disease, mast cells infiltrate the thyroid gland and then degranulate.[ref] Animal studies show that hypothyroidism (low thyroid hormone levels) increases the number of mast cells by up to 4.5-fold