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Mechanisms underlying drug-induced ototoxicity The possible mechanisms by which ototoxic agents can influence auditory function are nerve demyelination, apoptosis via caspase cascade, glutamate toxicity, ROS overload, DNA/RNA damage, inhibition of mitochondrial protein synthesis, inner ear hypo-perfusion and ion disturbance on the background of gene mutations, and increased permeability of triggered drugs (Fig

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Incorporating these glutathione-rich foods into your diet can contribute significantly to your overall health and well-being

This recycling process helps maintain redox homeostasis , the carefully controlled balance between oxidation and reduction reactions

Non-responders exist in every treatment population