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However, whether sustained NNMT inhibition beyond 12 weeks affects liver function in humans is unknown baseline and periodic monitoring of liver enzymes is recommended for use beyond published trial durations

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This approach is often used in tightly controlled experiments where consistency and simplicity are prioritised

Therefore, in these cases, vitamin B12 may be administered via intramuscular injections

If left untreated, vitamin B12 deficiency can cause neurological changes, such as numbness or tingling in the hands and feet

Joe Schwarcz (via McGill University)