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Patients should be aware that severe or progressive cold intolerance especially when accompanied by significant fatigue, constipation, dry skin, hair loss, or unexplained weight gain despite continued GLP-1 therapywarrants investigation for hypothyroidism or other conditions
However, varying the length of grace period had a less pronounced effect on the findings when assessing the proportion of patients with ongoing treatment (proportion of patients covered [31])
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Zinc supplementation may also not be appropriate for those with HIV/AIDS, those taking antibiotics or penicillamine (Cuprimine, Depen), or those with renal (kidney) dysfunction
