IL-18 acts in synergy with IL-12 to stimulate T cells production of IFN-, which in turn stimulates synovial macrophages to produce TNF- and IL-1, leading to joint inflammation and cartilage destruction (79)
This solution is Research Use Only (RUO), not intended for medical use and is not approved for diagnostic or therapeutic applications or in neonates
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South Florida patients dealing with the combined demands of year-round activity, heat-related recovery challenges, and high training volume are a patient population we understand well
Administration routes tested included both intravenous injection and oral formulations delivered as capsules or tablets