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In agreement, Matt Kaeberlein, PhD, professor of pathology at UW Medicine and CEO of Optispan said: Its disappointing but not particularly surprising that Novo Nordisks trials failed to show a slowing of Alzheimers progression with semaglutide
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More details are needed on the trials to give it proper consideration, including examination of safety aspects The one thing to caution is we do not know to what extent the weight loss effects of semaglutide as opposed to its other direct effects on blood vessels or the heart account for the 20 per cent reduction in cardiovascular events
The goal is often to adopt a caloric intake that you can sustain moving forward around 500750 calories below what your body needs to maintain weight (or whatever your healthcare provider recommends)
N Engl J Med (1992) 326:131622
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