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When administered in higher doses through injections, it is believed to reduce melanin production, leading to lighter skin tone over time

Protein Cell 9 , 145151 (2018)

inhibition accelerates its proteasomal degradation and suppresses adipocyte differentiation

Eur J Pediatr 152:244249

These can often be managed with simple measures (e.g., analgesic for headache, proper injection technique for site pain)