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Most short-term side effects (especially GI symptoms like nausea, vomiting, diarrhea, constipation) tend to improve over days to a few weeks as the body adjusts

European Journal of Clinical Pharmacology

Akkermansia muciniphila secretes P9 protein, which directly stimulates GLP-1 production from intestinal L cells

However, the small number ( n = 5) of pediatric patients and missing dosing information in most instances limit generalizability to the pediatric population

Prawitt D, Monteilh-Zoller MK, Brixel L et al (2003) TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i

Do not take during pregnancy or while nursing