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In Southeast Asia, where high rates of patch test positivity have been documented, there is still uncertainty regarding its clinical utility, as many patients face barriers in implementing avoidance strategies [5]
Lu, Y., Wu, D., Wang, X., Ward, S
Although the direct involvement of trained immunity remains to be confirmed, high-risk plaques produce higher levels of proinflammatory cytokines and chemokines than low-risk, stable plaques (108)
Veran et al., 2012
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