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Residues Y239 (TM5), Y358 (TM7) and F443 (TM10) all positioned ideally to form strong cation-\(\pi\) interactions, with nearby residues Y211, F359, Y387 and Y447 positioned within reasonable distance to form weak cation-\(\pi\) interactions

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The results indicated that ipamorelin evoked significant increases in insulin secretion at varying concentrations