The "IV" stands for intravenous, which just means "into the vein." It sounds intimidating if you've never done it, but most people describe it as a tiny pinch at the start, and then nothing
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Preincubation of heart mitochondria of GSH-treated old animals with inhibitor CsA (10 5 mol/L) almost completely prevented Ca 2+ -induced mitochondrial swelling, which indicates the association of this process with mPTP opening (Figure 2A)

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