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The latter is a competitor of 2-Oxoglutarate-dependent dioxygenases such as Ten-eleven translocation methylcytosine dioxygenase and therefore induces DNA hydroxymethylation and gene upregulation 52
De la Rosa, A., G
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As well as general chaperone activity, PDI family members possess oxidoreductase activity, which mediates the formation of protein disulfide bonds by cysteine residues located within its active site
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