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However, research is currently being done to explore whether it can be modified so as to not cross the blood-brain barrier
You shouldnt worry about this though because, as the researchers have shown, it improves your insulin function anyway, favors fat burning, and prevents carbohydrate-driven weight gain
Zhang, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 247, (2021) 119145
This includes people with gastroparesis, severe reflux, chronic constipation, inflammatory bowel disease, previous bariatric surgery, or recurrent vomiting
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