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Although additional studies are required to clarify the molecular mechanisms responsible for hyperhomocysteinemia-induced vascular disorders, there is evidence that the direct cytotoxicity of markedly elevated homocysteine and/or of its oxidized by-products (homocysteine thiolactone, homocysteine sulfinic acid, and homocysteic acid) damages endothelial cells (Dudman et al, 1991

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Tri-Fortify Orange contains ingredients derived from soy and tree nuts (coconut)

Measure against baseline weekly

Provides access to a dedicated Care Team for medication guidance, dose adjustments, and side-effect management