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doi: 10.1016/S0140-6736(18)30474-4 32 Neuschwander-TetriBALoombaRSanyalAJLavineJEVan NattaMLAbdelmalekMFet al
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The relatively short half-life, compared with longer-acting compounds in the broader GH-axis class, is part of why Ipamorelin produces a pulsatile, physiologically patterned GH release rather than a sustained elevation, which is one of the reasons it remains a preferred reference tool for studying pulsatile GH secretion patterns
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