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Because these peptides represent a fundamental shift in how we approach body composition, metabolic health, and longevity

Chantalat, E., Valera, C., Vaysse, C., Noirrit, E., Rusidze, M., Weyl, A., Vergriete, K., Buscail, E., Lluel, P., Fontaine, C., Arnal, F., & Lenfant, F

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Therefore, while aware that the pharmacological modulation of the NRF2/ARE pathway could undeniably offer new therapeutic opportunities for diseases related to OS, we should at the same time consider that most of the currently known activators of NRF2 are not particularly specific, leading to an increased risk of off target toxic effects

doi: 10.3389/fendo.2025.1568059 Received 28 January 2025 Accepted 10 April 2025 Published 30 April 2025 Volume 16 - 2025 Edited by Joao Dts Anselmo, Hospital do Divino Esprito Santo, Portugal Reviewed by Lucile Butruille, Musum National dHistoire Naturelle, France Updates Copyright 2025 Khudair, Khudair, Niinuma, Habib and Butler