An overflow of glutamate (the main endogenous excitatory amino in brain, at concentration of 515 mmol glutamate per kg body weight, higher than of any other neurotransmitter) is implicated in major psychiatric illnesses [1, 24,25,26]
It further reveals how current advances in triple agonists and oral formulations promise to further lower barriers to treatment and enhance therapeutic outcomes
And it is related to cholesterol metabolism genes such as LXR, ATP-binding cassette transporter A1 (ABCA1), ATP-binding cassette G1 (ABCG1), acyl-coenzyme A oxidase 1 (ACOX1), apolipoprotein AI (apo AI) (Fig
Diet pills, caffeine, laxatives, and others have been around for a long time, but with the emergence of GLP-1s, more reports of disordered eating have surfaced
Cost Reduction Some online conversations promote microdosing as a potentially cost-effective way to stretch medicationtaking less means there will be more left over for the next dose
Most side effects improve with time, the right dosing schedule, and simple lifestyle habits