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Plos One 2010 5:e9508
Concurrently, curcumin enhances neuroplasticity by upregulating BDNF/TrkB signaling and activating ERK/CREB pathways, thereby reversing synaptic deficits and promoting neural repair
Saleh H, Salama M, Hussein RM
There are well over 100 different nutrients, phytonutrients, and related dietary supplement ingredients thought to function as antioxidants or detoxification enhancing agents, at least in part, because of their ability to up-regulate Nrf2 activation
Neurochem Res 22:727733 Li X, Wallin C, Weber SG, Sandberg M (1999) Net efflux of cysteine, glutathione and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glutamyl transpeptidase
Taken together, the clinical and preclinical studies summarized in Table X indicate that microbiota-targeted interventions generally produce modest but clinically measurable improvements rather than disease remission
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