In ATTAIN-2 , which specifically studied people with both obesity and type 2 diabetes (a group for whom weight loss is known to be harder), participants on the highest dose lost an average of 10.5% of body weight (about 23 lbs) over 72 weeks, while also reducing A1C by an average of 1.8%
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Eur J Endocrinol 176:685693 Khalid SI, Omotosho PA, Spagnoli A, Torquati A (2020) Association of Bariatric Surgery With Risk of Fracture in Patients With Severe Obesity
However, studies have also shown that it does not improve sleep in individuals with insomnia
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