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Nausea and Vomiting Nausea is by far the most common side effect people experience when beginning GLP-1s
For the Schilling test flushing dose, 1000mcg should be administered IM
Reported side effects include: Severe digestive problems, which may lead to acute kidney injury Gallbladder problems Pancreatitis Risk of thyroid cancer Severe allergic reaction In people with pre-existing kidney conditions, symptoms such as diarrhoea, nausea, and vomiting may lead to dehydration, potentially worsening kidney function
Potential benefits include: Reduced incidence of osteoarthritis Lower burden of chronic spine pain Improved mobility and functional outcomes Reduced healthcare costs associated with degenerative disease For clinicians in pain medicine , recognizing the role of metabolic therapies will be increasingly essential
Appetite and hunger changes At 5mg, most people experience noticeable appetite suppression within the first 1-2 weeks
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