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FDA.gov (2026) 12

Warnings: Patients with early Leber's disease (hereditary optic nerve atrophy) may experience severe and rapid optic atrophy when treated with vitamin B12. Additionally, treating severe megaloblastic anemia with vitamin B12 can lead to fatal hypokalemia due to increased erythrocyte potassium requirements

PMID 28660890

While B12 is important for everyone, certain populations may benefit more from regular B12 supplementation via injections: Older Adults With age, the bodys ability to absorb B12 from food diminishes due to decreased stomach acid or conditions like atrophic gastritis

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