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The transcription regulator, forkhead box class O isoforms 4 (FOXO4), maintains the viability of senescent cells by localizing adjacent to p53-pS15 to prevent the nuclear exclusion of active p53-pS15 to mediate apoptosis 11
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These comparisons increased the robustness of our findings, especially since previous studies have shown that metformin and other GLP-1RAs are beneficial for Alzheimers disease, she further notes Our study provides promising real-world evidence suggesting that semaglutide is beneficial in preventing or slowing the development of Alzheimers disease, added Xu
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