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Rapid weight loss can contribute to muscle loss, whereas a slower reduction in body fat may help preserve lean muscle mass

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Table 1: Units of Insulin Glargine and Micrograms of Lixisenatide in Each Dosage of SOLIQUA 100/33 Titration Of SOLIQUA 100/33 After starting with the recommended dosage of SOLIQUA 100/33, [see DOSAGE AND ADMINISTRATION ], titrate the dosage upwards or downwards by two to four units (see Table 2) every week based on the patients metabolic needs, blood glucose monitoring results, and glycemic control goal until the desired fasting plasma glucose is achieved

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