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However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage

Also, some medications can interfere with B12 absorption

A 2020 study found that those with vitamin B12 deficiency may present with cognitive disorder, though the deficiency was not shown to be a direct risk factor for cognitive decline ( However, results have been mixed and treatment with vitamin B12 wasnt effective at improving brain function in people with normal brain function ( Depression Its been suggested that there may be a link between low vitamin B12 levels and depression

How to Switch from Pills to Injections If you have been taking oral supplements but still feel tired, foggy, or "off," it may be worth reevaluating, ideally starting with a test rather than a guess

Older adults, vegans and vegetarians, and people on long-term acid-reducing medication often run on the lower end of optimal range without obvious symptoms

Can I self-administer Vitamin B12 injections