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Additionally, intracerebroventricular delivery of Ex-4 has been found to dose-dependently attenuate cue-evoked dopamine activity, further underscoring the direct influence of GLP-1R signaling on neural circuits governing reinforcement and motivation (Konanur et al., 2020)

IGF-1 increases cardiac output, stroke volume, contractility, and ejection fraction, aiding recovery after myocardial infarction

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Features of SIPS include increased senescence-associated -galactosidase (SA--Gal) activity, appearance of senescence-associated heterochromatin foci (SAHF), cell growth arrest, and increased expression of senescence-associated genes 11,34

L-carnitine accelerates ATP production from fatty acid oxidation by facilitating the transport of fatty acids to the mitochondria [33]