The dual agonism is why tirzepatide produces greater weight loss than semaglutide, a selective GLP-1 agonist, as seen in trials comparing the two agents
Comorbidities such as cardiovascular disease, sleep apnea, or uncontrolled diabetes change priorities: reduce hypoglycemia risk, avoid volume depletion, and maintain glycemic targets that fit the procedures risk profile
Ready to get approved
Supports immune functions
Ozempic is paving the way for other GLP-1 drugs to treat conditions beyond kidney disease The FLOW trial results, along with the recent announcement that Wegovy is approved to reduce cardiovascular risk in people with obesity, are the latest indications that these drugs have benefits for conditions beyond their original intended treatment of type 2 diabetes
This reflective process is part of the therapeutic container we create around any medication with the potential to shape long-term behavior and self-perception