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These medications work by influencing hormones that regulate appetite and blood sugar, leading to reduced calorie intake and increased feelings of fullness
Visceral adipose tissue overrelease free fatty acids, proinflammatory cytokines (including TNF- and IL-6), and dysregulated adipokines (manifested as increased leptin and decreased adiponectin levels), collectively establishing a state of chronic low-grade inflammation (7173)
Consequently, identifying drugs that boost mitochondrial function and glucose oxidation to address the energy deficiency in HF represents a significant challenge 13
Electrolyte imbalances can also play a role
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