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Efficacy and safety of once-weekly semaglutide 1.0 Mg vs once-daily liraglutide 1.2 Mg as add-on to 13 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 10)

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Typical oral doses range from 100500 mg daily in divided doses, though tolerance and liver safety must be monitored closely, especially in patients with compromised hepatic function