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Although the aforementioned human studies provide important insights into the role of PYY in human metabolism, there are notable inconsistencies within the existing evidence, and these studies themselves have several key limitations that warrant cautious interpretation

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Exp Biol Med (Maywood) (2017) 242:121426

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The main sources of ROS under physiological conditions include the mitochondrial respiratory chain, peroxisomes, NADPH oxidase (NOX), and lipoxygenase (ALOX), and additional ROS-producing enzymes, such as cyclooxygenases (COXs) and cytochrome p450s (CYPs) [12, 13]

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