Impurities, synthesis-related fragments, and incorrect amino acid sequences can act as catalysts, accelerating the degradation process once the peptide is reconstituted
Although the contribution of an excessive intake of methionine has not been clinically proven, folate deficiency (associated or not with the thermolabile mutation of MTHFR) and vitamin B 6 deficiency (perhaps associated with heterozygosity for CBS deficiency or with methionine excess) would be strongly involved in the incidence of cardiovascular disease associated with moderate hyperhomocysteinemia
Jain and Yong, 2021)
Cavallini G, Biagiotti G, Koverech A, Vitali G
Also, studies have shown that the average avocado consumer is actually lower in body weight and body mass index than the avocado non-consumer
These are typically unavoidable and permanent, but do fade in appearance over time