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IV infusion (clinic-based) Protocol: Continuous daily supplementation -- typically 250-1000 mg NMN or 300-600 mg NR per day Rationale: NAD+ depletion is continuous, requiring ongoing replenishment to maintain elevated levels Requirements: No special handling for oral supplements

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Far longer than the immediate degradation most researchers fear when they discover a vial left out overnight

In the upper part of its course, the sciatic nerve lies deep in the gluteus maximus muscle and rests on the posterior surface of the ischium ( Figures 3 and 4 )

Administer by intramuscular injection