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21 The patient in the scenario above also was determined to have a previously undiagnosed OTC deficiency on her post-mortem exam

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Insulin resistance (an impaired response to insulin that results in elevated glucose levels) affects around 65-70% of women with PCOS, and for those also living with obesity, that number climbs to 70-80%

If you have sudden or irregular pigmentation, or if your pigmentation is persistent, then you should seek the care of a specialist