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Furthermore, treatment with sitagliptin and saxagliptin did not diminish the risk of serious adverse renal events, as measured by a doubling of serum creatinine or the need for renal replacement therapy

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Diabetes Therapy, 2021 A meta-analysis of cardiovascular outcomes trials showing that GLP-1 receptor agonists improve heart health in patients with type 2 diabetes, with dosing levels influencing tolerability and side effect profiles

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Pharmacotherapy of Obesity: An Update on the Available Medications and Drugs Under Investigation