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Why 1:1 Specifically Given the complementary-mechanisms framing, the natural design question is: should the ratio be 1:1, or should one component dominate
Depressed patients are often characterized by elevated blood cortisol levels and changes in the circadian secretion of this hormone, an increased number of corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamic paraventricular nucleus (PVN), as well as an impairment in a negative feedback mechanism, which can be measured in the dexamethasone suppression test [70, 71]
Smith RN, Agharkar AS, Gonzales EB
Many ASD characteristics require continuous support over a lifetime
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Having a system removes the cognitive load from what should be a simple weekly routine
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