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This is based on the efficacy estimand applied to the trial data

Over time, that can turn mild GLP-1 tiredness into something that feels constant

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10.1016/j.cmet.2023.11.009 85 XuR.LiuB.ZhouX

However, clinical trials on the effect of supplemental B vitamins or antioxidant vitamins on memory performance are limited and their findings are inconclusive