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these medications may need dose adjustment Increased heart rate, typically a modest elevation Dehydration risk, especially with persistent vomiting or poor fluid intake, which can lead to acute kidney injury According to MHRA guidance, rare but serious adverse effects include acute pancreatitis (inflammation of the pancreas), gallbladder disease including cholelithiasis (gallstones), and thyroid C-cell tumours (observed in rodent studies

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Its just a coincidence that they found an effect in diabetes first. Kariya and other companies are now pursuing the use of these drugs to treat neurodegeneration

In aqueous solution, the linker forms a covalent bond with cysteine residue 34 of plasma albumin, anchoring the peptide to a long-circulating carrier protein