The first 2 to 4 pounds of weight loss in the first two weeks is mostly fluid
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Musio A, Selicorni A, Focarelli ML, Gervasini C, Milani D, Russo S, et al
The Risk of Replacing Treatment If a patient with a severe autoimmune condition, requiring strong medication, replaces their treatment with GLP-1 agonists, they risk a significant worsening of their condition
Gastrointestinal Symptoms Nausea, bloating, and gastrointestinal discomfort are common side effects of GLP-1 medications, particularly early in treatment or after dose increases
Sabatino A, Cuppari L, Stenvinkel P, Lindholm B, Avesani CM