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These two characteristics make it inherently unsuitable for standard topical delivery: it degrades before it absorbs, and it repels the lipid-rich skin barrier

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However, a few contrary reports suggest that IL-6 deficient mice lacking the expression of cytoprotective heat shock proteins (HSPs) would be more susceptible to APAP hepatotoxicity [193]

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Phase II detoxification is the process by which the glutathione glutathione binds to xenobiotics (toxins, drugs, pollutants) via the enzyme glutathione-S-transferase (GST)