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It means that either human evidence confirms serious risk OR that animal data suggests potential serious risk warranting caution until human data accumulates

28 The stability of the human DBD is relatively poor, and it can dissolve at temperatures slightly above body temperature, which affects the stability of the full-length p53 protein

This can exacerbate symptoms in individuals who already have other pre-existing digestive problems

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They increase PGE, a key repair molecule PGE helps calm inflammation and encourage tissue repair